Tags: defect

MDR1 gene & Collies

MDR1 (or Multi-Drug Resistant protein gene) The MDR1 gene protects the brain by ensuring that any harmful chemical are transported AWAY from the brain.  In some dogs who are members of the herding varieties such as Collies and Australian Shepherds, a mutation in this gene causes extreme reactions to various drugs including Ivermectin (found in some heart worm […]